h_mcmc_get_hierarchical_data

<a href="https://lifecycle.r-lib.org/articles/stages.html#experimental"><img src="figures/lifecycle-experimental.svg?package=crmPack&version=2.2.1" alt="[Experimental]"></a>
Prepares the data list consumed by the dynamically compiled hierarchical JAGS
model. Arm-specific data are renamed with arm-specific prefixes so they align
with the generated model code.

internal

Implements a wide range of dose escalation
designs. The focus is on model-based designs, ranging from classical and
modern continual reassessment methods (CRMs) based on dose-limiting toxicity
endpoints to dual-endpoint designs taking into account a biomarker/efficacy
outcome. Bayesian inference is performed via MCMC sampling in JAGS, and it is easy
to setup a new design with custom JAGS code. However, it is also possible to
implement 3+3 designs for comparison or models with non-Bayesian estimation.
The whole package is written in a modular form in the S4 class system, making it
very flexible for adaptation to new models, escalation or stopping rules.
Further details are presented in
Sabanés Bové et al. (2019) <doi:10.18637/jss.v089.i10>.

Daniel Sabanes Bove

crmPack

Object-Oriented Implementation of Dose Escalation Designs

Daniel Sabanés Bové

Wai Yin Yeung

Burak Kuersad Guenhan

Giuseppe Palermo

Thomas Jaki

Jiawen Zhu

Ziwei Liao

Dimitris Kontos

Marlene Schulte-Goebel

Doug Kelkhoff

Oliver Boix

Robert Adams

Clara Beck

John Kirkpatrick

Wojciech Wójciak

Guanya Peng

Prerana Chandratre

F. Hoffmann-La Roche AG 

Merck Healthcare KGaA 

Bayer AG 

RPACT GmbH 

h_mcmc_get_hierarchical_data function

<dl><dt>model</dt>
<dd>(<code>HierarchicalModel</code>) hierarchical model object.</dd>
<dt>data</dt>
<dd>(<code>HierarchicalData</code>) hierarchical data object.</dd>
<dt>from_prior</dt>
<dd>(<code>flag</code>) should only prior-related inputs be returned?</dd></dl>

Arguments

<a href='https://lifecycle.r-lib.org/articles/stages.html#experimental'><img src='figures/lifecycle-experimental.svg' alt='[Experimental]' /></a>
Prepares the data list consumed by the dynamically compiled hierarchical JAGS
model. Arm-specific data are renamed with arm-specific prefixes so they align
with the generated model code.

Flatten HierarchicalData into JAGS Input for a HierarchicalModel — h_mcmc_get_hierarchical_data

<dl>

<dt>model</dt>
<dd>(<code>HierarchicalModel</code>) hierarchical model object.</dd>


<dt>data</dt>
<dd>(<code>HierarchicalData</code>) hierarchical data object.</dd>


<dt>from_prior</dt>
<dd>(<code>flag</code>) should only prior-related inputs be returned?</dd>

</dl>

Flatten <code>HierarchicalData</code> into JAGS Input for a <code>HierarchicalModel</code>

h_mcmc_get_hierarchical_data: Flatten `HierarchicalData` into JAGS Input for a `HierarchicalModel`

Description

Usage

Value

Arguments