ppi_intersection

Function to allow users to choose the intersection of stringdb and biogrid
Only works with the human PPI. min_score parameter only applies to strindb

Provides a general toolkit for drug target identification. We include functionality to reduce large graphs to subgraphs and prioritize nodes. In addition to being optimized for use with generic graphs, we also provides support to analyze protein-protein interactions networks from online repositories. For more details on core method, refer to Weaver et al. (2021) <https://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1008755>.

Davis Weaver

crosstalkr

Analysis of Graph-Structured Data with a Focus on
Protein-Protein Interaction Networks

ppi_intersection function

<dl><dt>cache</dt>
<dd>A filepath to a folder downloaded files should be stored</dd>
<dt>min_score</dt>
<dd>minimum connectivity score for each edge in the network.</dd>
<dt>edb</dt>
<dd>ensemble database object</dd></dl>

Arguments

Function to allow users to choose the intersection of stringdb and biogrid
Only works with the human PPI. min_score parameter only applies to strindb — ppi_intersection

<dl>

<dt>cache</dt>
<dd>A filepath to a folder downloaded files should be stored</dd>


<dt>min_score</dt>
<dd>minimum connectivity score for each edge in the network.</dd>


<dt>edb</dt>
<dd>ensemble database object</dd>

</dl>

ppi_intersection: Function to allow users to choose the intersection of stringdb and biogrid Only works with the human PPI. min_score parameter only applies to strindb

Description

Usage

Value

Arguments