The csaw package is designed for de novo detection of differentially bound regions from ChIP-seq data.
It provides methods for window-based counting, normalization, filtering and statistical analyses via edgeR.
The user guide for this package can be obtained by running this function.For non-Windows operating systems, the PDF viewer is taken from Sys.getenv("R_PDFVIEWER").
This can be changed to x by using Sys.putenv(R_PDFVIEWER=x).
For Windows, the default viewer will be selected to open the file.
Note that the user's guide is not a true vignette as it is not generated using Sweave when the package is built.
This is due to the time-consuming nature of the code when run on realistic case studies.