TTC_ic_adtneh2_log

Produce confidence interval of the time TTC with log method

internal

Fits a variety of cure models using excess hazard modeling methodology such as the mixture model proposed by Phillips et al. (2002) <doi:10.1002/sim.1101> The Weibull distribution is used to represent the survival function of the uncured patients; Fits also non-mixture cure model such as the time-to-null excess hazard model proposed by Boussari et al. (2020) <doi:10.1111/biom.13361>.

Juste Goungounga

curesurv

Mixture and Non Mixture Parametric Cure Models to Estimate Cure
Indicators

Judith Breaud

Olayide Boussari

Valerie Jooste

TTC_ic_adtneh2_log function

<dl><dt>z_alpha</dt>
<dd>Covariates matrix acting on parameter alpha of the density of
time-to-null excess hazard model</dd>
<dt>z_tau</dt>
<dd>Covariates matrix acting on time-to-null parameter.</dd>
<dt>xmax</dt>
<dd>time max at which Pi(t) is calculated.</dd>
<dt>object</dt>
<dd>ouput from a model implemented in curesurv</dd>
<dt>epsilon</dt>
<dd>value fixed by user to estimate the TTC \(\text{Pi}(t)\geq (1-\epsilon)\).
By default \(\epsilon = 0.05\).</dd>
<dt>level</dt>
<dd><code>1-alpha/2</code>-order quantile of a normal distribution</dd>
<dt>TTC</dt>
<dd>time to cure TTC,if NULL then calculated</dd>
<dt>varTTC</dt>
<dd>variance of time to cure ,if NULL then calculated</dd></dl>

Arguments

Juste Goungounga, Judith Breaud, Eugenie Blandin, Olayide Boussari, Valerie Jooste

Author

TTC_ic_adtneh2_log function — TTC_ic_adtneh2_log

<dl>

<dt>z_alpha</dt>
<dd>Covariates matrix acting on parameter alpha of the density of
time-to-null excess hazard model</dd>


<dt>z_tau</dt>
<dd>Covariates matrix acting on time-to-null parameter.</dd>


<dt>xmax</dt>
<dd>time max at which Pi(t) is calculated.</dd>


<dt>object</dt>
<dd>ouput from a model implemented in curesurv</dd>


<dt>epsilon</dt>
<dd>value fixed by user to estimate the TTC \(\text{Pi}(t)\geq (1-\epsilon)\).
By default \(\epsilon = 0.05\).</dd>


<dt>level</dt>
<dd><code>1-alpha/2</code>-order quantile of a normal distribution</dd>


<dt>TTC</dt>
<dd>time to cure TTC,if NULL then calculated</dd>


<dt>varTTC</dt>
<dd>variance of time to cure ,if NULL then calculated</dd>

</dl>

TTC_ic_adtneh2_log: TTC_ic_adtneh2_log function

Description

Usage

Arguments

Author

References