is.fixed: Test to see if two populations are fixed at a given locus
Description
This script compares two percent allele frequencies
and reports TRUE if they represent a fixed difference, FALSE otherwise.
Usage
is.fixed(s1, s2, tloc = 0)
Arguments
s1
-- percentage SNP allele frequency for the first population [required]
s2
-- percentage SNP allele frequency for the second population [required]
tloc
-- threshold value for tolerance in when a difference is regarded as fixed [default 0]
Value
TRUE (fixed difference) or FALSE (alleles shared) or NA (one or both s1 or s2 missing)
Details
A fixed difference at a locus occurs when two populations share no alleles, noting that SNPs are biallelic (ploidy=2).
Tollerance in the definition of a fixed difference is provided by the t parameter. For example, t=0.05 means
that SNP allele frequencies of 95,5 and 5,95 percent will be reported as fixed (TRUE).