is.fixed: Tests if two populations are fixed at a given locus
Description
This script compares two percent allele frequencies
and reports TRUE if they represent a fixed difference, FALSE otherwise.
Usage
is.fixed(s1, s2, tloc = 0)
Arguments
s1
Percentage SNP allele or sequence tag frequency for the first
population [required].
s2
Percentage SNP allele or sequence tag frequency for the second
population [required].
tloc
Threshold value for tolerance in when a difference is regarded as
fixed [default 0].
Value
TRUE (fixed difference) or FALSE (alleles shared) or NA (one or both
s1 or s2 missing)
Details
A fixed difference at a locus occurs when two populations share no alleles,
noting that SNPs are biallelic (ploidy=2).
Tolerance in the definition of a fixed difference is provided by the t
parameter. For example, t=0.05 means that SNP allele frequencies of 95,5 and
5,95 percent will be reported as fixed (TRUE).