ccl4data

The results of a closed chamber experiment to determine metabolic
    parameters for CCl4 (carbon tetrachloride) in rats.

Functions that solve a system of first-order ordinary 
             differential equations (ODE) and of differential algebraic 
             equations (DAE).
             The functions provide an interface to the FORTRAN functions
             lsoda, lsodar, lsode, lsodes, dvode and daspk. 
             The package also contains routines designed for solving 
             uni-and multicomponent 1-D and 2-D reactive transport models.

R. Setzer

deSolve

General solvers for ordinary differential equations 
       (ODE) and for differential algebraic equations (DAE)

ccl4data function

This data frame contains the following columns:
    <item>time. The time (in hours after starting the experiment)
    <item>initconc. initial chamber concentration (ppm)
    <item>animal. This is a repeated measures design; this variable
        indicates which animal the observation pertains to
    <item>ChamberConc. chamber concentration at <code>time</code>, in ppm</item>
<source>Evans, et al. 1994 Applications of sensitivity analysis to a
  physiologically based pharmacokinetic model for carbon tetrachloride in
  rats.  Toxicology and Applied Pharmacology 128: 36 -- 44.
<examples>plot(ChamberConc ~ time,data=ccl4data,xlab="Time (hours)",
         xlim=range(c(0,ccl4data$time)),
         ylab="Chamber Concentration (ppm)",log="y")
ccl4data.avg&lt;-aggregate(ccl4data$ChamberConc,
                        by=ccl4data[c("time","initconc")],mean)
points(x ~ time,data=ccl4data.avg,pch=16)</examples>     
<keyword>datasets</keyword></item></item></item>

ccl4data: Closed chamber study of CCl4 metabolism by rats.

Description

Usage

Arguments

format