updateW_GR: Updates the weights matrix
Description
Determines what proportion of what signature, when added to the current
weights matrix, results in the lowest sum-squared error
Usage
updateW_GR(tumor, signatures, w, signatures.limit, bound = 100)
Arguments
tumor
Actual trinucleotide context fractions
signatures
Signatures matrix
signatures.limit
Number of signatures to limit the search to
Value
Returns an updated weights matrix