autismDeNovos


de novo variants found in 1,078 autism trios, published in Nature Genetics(http://www.nature.com/doifinder/10.1038/ng.3050)


datasets

An integrated toolset for the analysis of de novo (sporadic)
genetic sequence variants. denovolyzeR implements a mutational model that
estimates the probability of a de novo genetic variant arising in each human
gene, from which one can infer the expected number of de novo variants in a
given population size. Observed variant frequencies can then be compared against
expectation in a Poisson framework. denovolyzeR provides a suite of functions
to implement these analyses for the interpretation of de novo variation in human
disease.

James Ware

denovolyzeR

Statistical Analyses of De Novo Genetic Variants

autismDeNovos function

A data frame with 1096 obs of 2 variables:
<dl> </dl>

autismDeNovos: de novo variants found in 1,078 autism trios

Description

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References