viewProbabilityTable

option to display table in wide format (default; one line per gene), or long format

format


Tabulates probability of <em>de novo</em> variant for each protein-coding variant class, for each gene.  Values are probability of a <em>de novo</em> variant per chromosome per generation.  i.e. expected number of de novos for a given gene/class = $p * 2 * nsamples$.


An integrated toolset for the analysis of de novo (sporadic)
genetic sequence variants. denovolyzeR implements a mutational model that
estimates the probability of a de novo genetic variant arising in each human
gene, from which one can infer the expected number of de novo variants in a
given population size. Observed variant frequencies can then be compared against
expectation in a Poisson framework. denovolyzeR provides a suite of functions
to implement these analyses for the interpretation of de novo variation in human
disease.

viewProbabilityTable: Displays underlying de novo probability tables

Description

Usage

Arguments