Provides a convenient framework to simulate, test, power, and visualize data for differential expression studies with lognormal or negative binomial outcomes. Supported designs are two-sample comparisons of independent or dependent outcomes. Power may be summarized in the context of controlling the per-family error rate or family-wise error rate. Negative binomial methods are described in Yu, Fernandez, and Brock (2017) tools:::Rd_expr_doi("10.1186/s12859-017-1648-2") and Yu, Fernandez, and Brock (2020) tools:::Rd_expr_doi("10.1186/s12859-020-3541-7").
Maintainer: Brett Klamer code@brettklamer.com (ORCID)
Authors:
Lianbo Yu lianbo.yu@osumc.edu (ORCID)