plot,dose,missing-method

the "y" argument is not used in the plot-method for "dose" object.

Choose plot or not; defaults to TRUE.

Indicate if the "dose" object includes the 95% credible interval for the posterior dose response plot; defaults to TRUE.

other arguments to the <code><a rd-options="=graphics" href="/link/plot.default?package=dfpk&version=3.5.1&to=%3Dgraphics" data-mini-rdoc="=graphics::plot.default">plot.default</a></code> function can be passed here.

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The graphical representation of dose escalation for each patient in the trial.

Statistical methods involving PK measures are provided, in the dose allocation process during a Phase I clinical trials. These methods, proposed by Ursino et al, (2017) <doi:10.1002/bimj.201600084>, enter pharmacokinetics (PK) in the dose finding designs in different ways, including covariates models, dependent variable or hierarchical models. This package provides functions to generate data from several scenarios and functions to run simulations which their objective is to determine the maximum tolerated dose (MTD).

Artemis Toumazi

dfpk

Bayesian Dose-Finding Designs using Pharmacokinetics (PK) for
Phase I Clinical Trials

Sarah Zohar

Moreno Ursino

Trustees of Columbia University

French National Institute of Health and Medical Research

plot,dose,missing-method function

other arguments to the <code><a rd-options='=graphics' href='plot.default'>plot.default</a></code> function can be passed here.

plot,dose,missing-method: The graphical representation of dose escalation for each patient in the trial.

Description

Usage

Arguments

References