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dfpk (version 3.5.1)

plot,scen,missing-method: The graphical representation of the drug's concentration in the plasma at time t after the drug administration.

Description

The graphical representation of the drug's concentration in the plasma at time t after the drug administration.

Usage

# S4 method for scen,missing
plot(x, y = NA, col = rainbow(length(x@doses)),
  xlab = "Time (hours)", ylab = "Concentration (mg/L)",
  main = "Pharmacokinetics: Concentration vs Time", ...)

Arguments

x

a "scen" object or a list of the selected trial from a "scen" object.

y

the "y" argument is not used in the plot-method for "scen" object.

col

the color argument to the plot.default function.

xlab

the label of x-axis.

ylab

the label of y-axis.

main

the title of the graph.

other arguments to the plot.default function can be passed here.

References

Ursino, M., et al, (2017) Dose-finding methods for Phase I clinical trials using pharmacokinetics in small populations, Biometrical Journal, <doi:10.1002/bimj.201600084>.

Toumazi, A., et al, (2018) dfpk: An R-package for Bayesian dose-finding designs using pharmacokinetics (PK) for phase I clinical trials, Computer Methods and Programs in Biomedicine, <doi:10.1016/j.cmpb.2018.01.023>.