show-methods

show,dosefinding-method

show,scen-method

show,dose-method

S4 Methods for function <code>show</code>.

methods

Statistical methods involving PK measures are provided, in the dose allocation process during a Phase I clinical trials. These methods, proposed by Ursino et al, (2017) <doi:10.1002/bimj.201600084>, enter pharmacokinetics (PK) in the dose finding designs in different ways, including covariates models, dependent variable or hierarchical models. This package provides functions to generate data from several scenarios and functions to run simulations which their objective is to determine the maximum tolerated dose (MTD).

Artemis Toumazi

dfpk

Bayesian Dose-Finding Designs using Pharmacokinetics (PK) for
Phase I Clinical Trials

Sarah Zohar

Moreno Ursino

Trustees of Columbia University

French National Institute of Health and Medical Research

show-methods function

<dl class="dl-horizontal"><dt><code>signature(object = "dosefinding")</code></dt><dd>S4 method to store and present the dose-finding results.</dd><dt><code>signature(object = "scen")</code></dt><dd>S4 method to store and present the simulated datasets.</dd><dt><code>signature(object = "dose")</code></dt><dd>S4 method to store and present the next recommended dose level in an ongoing trial.</dd>
</dl>

Methods

S4 Methods for Function <code>show</code> — show-methods

S4 Methods for Function <code>show</code>

show-methods: S4 Methods for Function `show`

Description

Arguments

Methods