diffloop: diffloop: A package for differential DNA loop calling from ChIA-PET data
Description
The diffloop package contains a suite of tools and S4 data objects to
efficiently facilitate the analysis of ChIA-PET datasets. Key features
include differential loop calling, visualization of looping in regions,
quality-control metrics, and principal component analysis across
experiments.diffloop classes
Three classes mostly comprise the methodology in diffloop
. First,
loops
is a basic structure that contains one or more ChIA-PET
experiments, loopfit
links an edgeR
fit to a loops
and currently has little functionality except for generating another
loops
object where per-loop summary statistics are added.