var_pi

Calculate multiple types of variances of DOOR probability

Statistical methods and related graphical representations for the Desirability of Outcome Ranking (DOOR) methodology. The DOOR is a paradigm for the design, analysis, interpretation of clinical trials and other research studies based on the patient centric benefit risk evaluation. The package provides functions for generating summary statistics from individual level/summary level datasets, conduct DOOR probability-based inference, and visualization of the results. For more details of DOOR methodology, see Hamasaki and Evans (2025) <doi:10.1201/9781003390855>. For more explanation of the statistical methods and the graphics, see the technical document and user manual of the DOOR 'Shiny' apps at <https://methods.bsc.gwu.edu>.

Yijie He

door

Analysis of Clinical Trials with the Desirability of Outcome
Ranking Methodology

Qihang Wu

Toshimitsu Hamasaki

var_pi function

<dl><dt>p1</dt>
<dd>Vector of DOOR outcome proportion distribution for group 1</dd>
<dt>p2</dt>
<dd>Vector of DOOR outcome proportion distribution for group 2</dd>
<dt>n1</dt>
<dd>Sample size of group 1</dd>
<dt>n2</dt>
<dd>Sample size of group 2</dd></dl>

Arguments

Variance of DOOR probability — var_pi

<dl>

<dt>p1</dt>
<dd>Vector of DOOR outcome proportion distribution for group 1</dd>


<dt>p2</dt>
<dd>Vector of DOOR outcome proportion distribution for group 2</dd>


<dt>n1</dt>
<dd>Sample size of group 1</dd>


<dt>n2</dt>
<dd>Sample size of group 2</dd>

</dl>

var_pi: Variance of DOOR probability

Description

Usage

Value

Arguments