drc (version 2.1-1)

heartrate: Heart rate baroreflexes for rabbits

Description

The dataset contains measurements of mean arterial pressure (mmHG) and heart rate (b/min) for a baroreflex curve.

Usage

data(heartrate)

source

Ricketts, J. H. and Head, G. A. (1999) A five-parameter logistic equation for investigating asymmetry of curvature in baroreflex studies, Am. J. Physiol. (Regulatory Integrative Comp. Physiol. 46), 277, 441--454.

Details

The dataset is an example of an asymmetric dose-response curve, that is not easily handled using the log-logistic or Weibull models (LL.4, LL.5, W1.4 and W2.4), whereas the baro5 model provides a nice fit.

Examples

## Fitting the baro5 model
heartrate.m1 <- drm(rate~pressure, data=heartrate, fct=baro5())
plot(heartrate.m1)