unique.tauSurface

Output of <code><a rd-options="" href="/link/getTauSurface?package=drugCombo&version=1.2.1" data-mini-rdoc="drugCombo::getTauSurface">getTauSurface</a></code>.

Further arguments, currently not used.

"unique" method to extract unique interaction index estimates from a 
"tauSurface" object in a tabular format.

Perform assessment of synergy/antagonism for drug combinations based
on the Loewe additivity model, following Harbron's approach (Statistics in
Medicine, 2010, <doi:10.1002/sim.3916>). The package allows flexible modeling
of the drug interaction index and supports "2-stage" estimation in addition
to "1-stage" estimation, including bootstrap-based confidence intervals.
The method requires data on the monotherapy responses and the package
accommodates both checkerboard and ray designs. Functions are available for
graphical exploration of model goodness-of-fit and diagnostics, as well as
for synergy/antagonism assessment in 2D and 3D.

Maxim Nazarov

drugCombo

Drug Interaction Modeling Based on Loewe Additivity Following
Harbron's Approach

unique.tauSurface function

Output of <code><a rd-options='' href='getTauSurface'>getTauSurface</a></code>.

unique.tauSurface: Unique method for "tauSurface" objects

Description

Usage

Arguments