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easyDifferentialGeneCoexpression (version 1.4)

Easily Performs Differential Coexpression Analysis

Description

A function that reads in the GEO code of a list of probesets or gene symbols, a gene expression dataset GEO accession code, the name of the dataset feature discriminating the two conditions for the differential coexpression, and the values of the two different conditions for the differential coexpression, and returns the significant pairs of genes/probesets with highest differential coexpression (p-value < 0.005). If the input gene list is made of gene symbols, this package associates the probesets to these gene symbols, if found. Platforms available: GPL80, GPL8300, GPL80, GPL96, GPL570, GPL571, GPL20115, GPL1293, GPL6102, GPL6104, GPL6883, GPL6884, GPL13497, GPL14550, GPL17077, GPL6480. GEO: Gene Expression Omnibus. ID: identifier code. The GEO datasets are downloaded from the URL .

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install.packages('easyDifferentialGeneCoexpression')

Monthly Downloads

8

Version

1.4

License

GPL-3

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Maintainer

Davide Chicco

Last Published

February 5th, 2024

Functions in easyDifferentialGeneCoexpression (1.4)

fromProbesetToGeneSymbol

Function that associates a gene symbol to a probeset for some Affymetrix platforms
easyDifferentialGeneCoexpression

Function that computes the differential coexpression of a list of probesets in a specific dataset and returns the most significant pairs
probesetRetrieval

Function that reads a CSV file of probesets or gene symbols and, in the latter case, it retrieves the original probesets
geoDataDownload

Function that downloads gene expression data from GEO, after checking the connection
geoPlatformAnnotationsDownload

Function that downloads the annotations of a GEO platform