assign_link_operator_value_to_equation

<p>string. The boolean equation in the form
\(Target *= (Activator or Activator or...)
and not (Inhibitor or Inhibitor or...)"\)</p>

equation

<p>Assign link operator value to boolean equation</p>

Analysis and visualization of an ensemble of boolean models for
biomarker discovery in cancer cell networks. The package allows to easily
load the simulation data results of the DrugLogics software pipeline which predicts synergistic drug
combinations in cancer cell lines (developed by the DrugLogics research group
in NTNU). It has generic functions that can be used to split a boolean model
dataset to model groups with regards to the models predictive performance (number of true
positive predictions/Matthews correlation coefficient score) or synergy prediction based on a given set
of gold standard synergies and find the average activity difference per network
node between all model group pairs. Thus, given user-specific thresholds,
important nodes (biomarkers) can be accessed in the sense that they make the
models predict specific synergies (synergy biomarkers) or have better
performance in general (performance biomarkers). Lastly, if the
boolean models have a specific equation form and differ only in their link operator,
link operator biomarkers can also be found.

John Zobolas

assign_link_operator_value_to_equation: Assign link operator value to boolean equation

Description

Usage

Arguments

Value