data.GST:
The data of GSTs family interaction on cancer.
Description
This data used the data from a meta-analysis included about 500 studies investigating the associations between GSTM1/GSTT1 and cancer, and saved the studies both reported the genotype of GSTM1 and GSTT1. Finally, there are 360 studies (375 populations) included in this data.
Usage
data("data.GST")
Arguments
Format
A data frame with 375 observations on the following 12 variables.
Study
the first author and published year in included studies.
Ethnicity
the ethnicity of each population.
Country
the location of study.
Cancer
the subtype of cancer in each study.
case.GSTM1.0
the number of GSTM1 functional type in cases.
ctrl.GSTM1.0
the number of GSTM1 null type in cases (risk type).
case.GSTM1.1
the number of GSTM1 functional type in controls.
ctrl.GSTM1.1
the number of GSTM1 null type in controls (risk type).
case.GSTT1.0
the number of GSTT1 functional type in cases.
ctrl.GSTT1.0
the number of GSTT1 null type in cases (risk type).
case.GSTT1.1
the number of GSTT1 functional type in controls.
ctrl.GSTT1.1
the number of GSTT1 null type in controls (risk type).
References
Fang J, Wang S, Zhang S, Su S, Song Z, Deng Y, et al. (2013) Association of the Glutathione S-Transferase M1, T1 Polymorphisms with Cancer: Evidence from a Meta-Analysis. PLoS ONE 8(11): e78707. doi:10.1371/journal.pone.0078707