data.RAS:
The data of RAS interaction on chronic kidney disease.
Description
This used the data from a meta-analysis included about 100 studies investigating the associations between ACE insertion/deletion (I/D) and chronic kidney disease, and re-collected the studies included AGT M235T information. Finally, there are 34 studies included in this data.
Usage
data("data.RAS")
Arguments
Format
A data frame with 34 observations on the following 12 variables.
Author
the first author in included studies.
Year
the published year in included studies.
Race
the race of each population.
Tyep
the subtype of chronic kidney disease in each study.
case.ACE.0
the number of I allele (rs4340) in cases.
case.ACE.1
the number of D allele (rs4340) in cases (risk allele).
ctrl.ACE.0
the number of I allele (rs4340) in controls.
ctrl.ACE.1
the number of D allele (rs4340) in controls (risk allele).
case.AGT.0
the number of M allele (rs699) in cases.
case.AGT.1
the number of T allele (rs699) in cases (risk allele).
ctrl.AGT.0
the number of M allele (rs699) in controls.
ctrl.AGT.1
the number of T allele (rs699) in controls (risk allele).
References
Lin C, Yang HY, Wu CC, Lee HS, Lin YF, Lu KC, et al. (2014) Angiotensin-Converting Enzyme Insertion/Deletion Polymorphism Contributes High Risk for Chronic Kidney Disease in Asian Male with Hypertension: A Meta-Regression Analysis of 98 Observational Studies. PLoS ONE 9(1): e87604. doi:10.1371/journal.pone.0087604