check.strong.surr

Calculates whether each individual has a strong surrogate, based on PTE results from Study A and a desired threshold.

internal

Provides functions for treatment effect estimation, hypothesis testing, and future study design for settings where the surrogate is used in place of the primary outcome for individuals for whom the surrogate is valid, and the primary outcome is purposefully measured in the remaining patients. More details are available in: Knowlton, R., Parast, L. (2024) ``Efficient Testing Using Surrogate Information," Biometrical Journal, 67(6): e70086, <doi:10.1002/bimj.70086>. A tutorial for this package can be found at <https://www.laylaparast.com/etsi>.

Layla Parast

etsi

Efficient Testing Using Surrogate Information

Rebecca Knowlton

check.strong.surr function

<dl> <dt>df</dt>
<dd>The dataframe to determine strong surrogacy.</dd> <dt>k</dt>
<dd>k, the threshold at which PTE &gt; k qualifies as a strong surrogate</dd> <dt>PTE.results</dt>
<dd>The PTE results (from the hetsurr::hetsurr.fun function) that should be used to determine strong surrogacy.</dd></dl>

Arguments

Calculates whether each individual has a strong surrogate, based on PTE results from Study A and a desired threshold. — check.strong.surr

<dl>

 <dt>df</dt>
<dd>The dataframe to determine strong surrogacy.</dd>

 <dt>k</dt>
<dd>k, the threshold at which PTE &gt; k qualifies as a strong surrogate</dd>

 <dt>PTE.results</dt>
<dd>The PTE results (from the hetsurr::hetsurr.fun function) that should be used to determine strong surrogacy.</dd>

</dl>

check.strong.surr: Calculates whether each individual has a strong surrogate, based on PTE results from Study A and a desired threshold.

Description

Usage

Value

Arguments