exampledataA

Provides functions for treatment effect estimation, hypothesis testing, and future study design for settings where the surrogate is used in place of the primary outcome for individuals for whom the surrogate is valid, and the primary outcome is purposefully measured in the remaining patients. More details are available in: Knowlton, R., Parast, L. (2024) ``Efficient Testing Using Surrogate Information," Biometrical Journal, 67(6): e70086, <doi:10.1002/bimj.70086>. A tutorial for this package can be found at <https://www.laylaparast.com/etsi>.

Layla Parast

etsi

Efficient Testing Using Surrogate Information

Rebecca Knowlton

exampledataA function

A data frame with 1000 observations from a treatment group and 1100 observations from a control group:<dl>
 <dt><code>A</code></dt>
<dd>the treatment assignment, where 1 indicates treatment and 0 indicates control</dd> <dt><code>W</code></dt>
<dd>the baseline covariate of interest</dd> <dt><code>S</code></dt>
<dd>the surrogate outcome</dd> <dt><code>Y</code></dt>
<dd>the primary outcome</dd> <dt><code>delta</code></dt>
<dd>the indicator for strong surrogacy, where 1 indicates strong and 0 indicates weak</dd> 
</dl>

Format

Example Data (Study A) — exampledataA

A data frame with 1000 observations from a treatment group and 1100 observations from a control group:<dl>
 <dt><code>A</code></dt>
<dd>the treatment assignment, where 1 indicates treatment and 0 indicates control</dd>

 <dt><code>W</code></dt>
<dd>the baseline covariate of interest</dd>

 <dt><code>S</code></dt>
<dd>the surrogate outcome</dd>

 <dt><code>Y</code></dt>
<dd>the primary outcome</dd>

 <dt><code>delta</code></dt>
<dd>the indicator for strong surrogacy, where 1 indicates strong and 0 indicates weak</dd>

 
</dl>

exampledataA: Example Data (Study A)

Description

Usage

Arguments

Format

Examples