relative_risk

relative_risk_table

order_filter

Calculate relative risks to be reported or plotted as dot plot

The remit of the European Clinical Trials Data Base (EudraCT <https://eudract.ema.europa.eu/> ), or ClinicalTrials.gov <https://clinicaltrials.gov/>, is to provide open access to summaries of all registered clinical trial results; thus aiming to prevent non-reporting of negative results and provide open-access to results to inform future research. The amount of information required and the format of the results, however, imposes a large extra workload at the end of studies on clinical trial units. In particular, the adverse-event-reporting component requires entering: each unique combination of treatment group and safety event; for every such event above, a further 4 pieces of information (body system, number of occurrences, number of subjects, number exposed) for non-serious events, plus an extra three pieces of data for serious adverse events (numbers of causally related events, deaths, causally related deaths). This package prepares the required statistics needed by EudraCT and formats them into the precise requirements to directly upload an XML file into the web portal, with no further data entry by hand.

Simon Bond

eudract

Creates Safety Results Summary in XML to Upload to EudraCT, or
ClinicalTrials.gov

Beatrice Pantaleo

relative_risk function

<dl><dt>safety</dt>
<dd>an object created by <code>safety_summary</code></dd>
<dt>type</dt>
<dd>a choice of "non_serious" (default) or "serious" as to which type of AE to report on</dd>
<dt>reference</dt>
<dd>character vector naming the reference arm for the calculations. 
Defaults to the first row of the safety$GROUP.</dd>
<dt>size</dt>
<dd>a number between 0-100, giving the size of the confidence interval. 
Default is 95.</dd>
<dt>digits</dt>
<dd>integer giving the number of significant figures to report to. Default of 3.</dd>
<dt>valid_estimates</dt>
<dd>a logical, which determines if only terms with valid estimates of relative risk are included in the table.
The alternative is to include terms with zeroes.</dd>
<dt>rel_risk</dt>
<dd>a relative risk object</dd>
<dt>threshold</dt>
<dd>a threshold on the percent scale, the max percentage for a term the incidence rate needs to exceed</dd></dl>

Arguments

Calculate relative risks to be reported or plotted as dot plot — relative_risk

<dl>

<dt>safety</dt>
<dd>an object created by <code>safety_summary</code></dd>


<dt>type</dt>
<dd>a choice of "non_serious" (default) or "serious" as to which type of AE to report on</dd>


<dt>reference</dt>
<dd>character vector naming the reference arm for the calculations. 
Defaults to the first row of the safety$GROUP.</dd>


<dt>size</dt>
<dd>a number between 0-100, giving the size of the confidence interval. 
Default is 95.</dd>


<dt>digits</dt>
<dd>integer giving the number of significant figures to report to. Default of 3.</dd>


<dt>valid_estimates</dt>
<dd>a logical, which determines if only terms with valid estimates of relative risk are included in the table.
The alternative is to include terms with zeroes.</dd>


<dt>rel_risk</dt>
<dd>a relative risk object</dd>


<dt>threshold</dt>
<dd>a threshold on the percent scale, the max percentage for a term the incidence rate needs to exceed</dd>

</dl>

relative_risk: Calculate relative risks to be reported or plotted as dot plot

Description

Usage

Value

Arguments

See Also

Examples