piecewiseExp_test_changepoint

This function implements the Wald test described in Goodman et al (2011) and applied in Fang &amp; Zheng (2011) to infer a change point in an estimated piecewise Exponential hazard function. Adjusts for sequential testing.

htest

Implements the hybrid framework for event prediction described in Fang & Zheng (2011, <doi:10.1016/j.cct.2011.05.013>). To estimate the survival function the event prediction is based on, a piecewise exponential hazard function is fit to the time-to-event data to infer the potential change points. Prior to the last identified change point, the survival function is estimated using Kaplan-Meier, and the tail after the change point is fit using piecewise exponential.

Kaspar Rufibach

eventTrack

Event Prediction for Time-to-Event Endpoints

piecewiseExp_test_changepoint function

<dl> <dt>peMLE</dt>
<dd>Piecewise Exponential hazard function estimate, as generated by <code>piecewiseExp_MLE</code>.</dd> <dt>alpha</dt>
<dd>Overall significance level. Will be adjusted for sequential testing internally, see function output.</dd></dl>

Arguments

Kaspar Rufibach (maintainer) <a href="/link/kaspar.rufibach%40roche.com?package=eventTrack&version=1.0.4" data-mini-rdoc="eventTrack::kaspar.rufibach@roche.com">kaspar.rufibach@roche.com</a>

Author

Wald test to infer change point in piecewise Exponential survival model — piecewiseExp_test_changepoint

<dl>

 <dt>peMLE</dt>
<dd>Piecewise Exponential hazard function estimate, as generated by <code>piecewiseExp_MLE</code>.</dd>

 <dt>alpha</dt>
<dd>Overall significance level. Will be adjusted for sequential testing internally, see function output.</dd>

</dl>

Kaspar Rufibach (maintainer) <a href='mailto:kaspar.rufibach@roche.com'>kaspar.rufibach@roche.com</a>

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piecewiseExp_test_changepoint: Wald test to infer change point in piecewise Exponential survival model

Description

Usage

Value

Arguments

Author

References

Examples