dlt_curve_d1classical

a numerical value indicating the true value of the parameter mtd.

a numerical value indicating the true value of the parameter rho.

a numerical value defining the proportion of expected patients
to experience a medically unacceptable, dose-limiting toxicity (DLT) if
administered the MTD.

theta

a numerical value defining the lower bound of the support of
the MTD.

min_dose

a numerical value defining the upper bound of the support of
the MTD.

max_dose

a numerical vector of doses that probability of DLT will
be calculated.

dose_set

Plot the DLT curve based on the EWOC classical model

An implementation of a variety of escalation with overdose control designs introduced by Babb, Rogatko and Zacks (1998) <doi:10.1002/(SICI)1097-0258(19980530)17:10%3C1103::AID-SIM793%3E3.0.CO;2-9>. It calculates the next dose as a clinical trial proceeds and performs simulations to obtain operating characteristics.

dlt_curve_d1classical: Plot the DLT curve based on the EWOC classical model

Description

Usage

Arguments