A data set containing the potency stability data (in % of label claim (LC))
of five batches of a drug product obtained over a 24 months period. A total
of \(n = 53\) independent measurements are available (corresponding to
data shown in Tables IV, VI and VIII in LeBlond et al. (2011)). Data in
Table IV (batches b2
, b5
and b7
) are compatible with a
common intercept / common slope (cics) model, data in Table VI (batches
b3
, b4
and b5
) with a different intercept / common slope
(dics) model and data in Table VIII (bathes b4
, b5
and
b8
) with a different intercept / different slope (dids) model.
data(exp1)
A data frame with 53 observations and 3 variables:
Factor with levels b2
, b3
, b4
, b5
,
b7
and b8
Numeric representing the time points of testing from the start (0 months) to the end (24 months) of the study.
Numeric of the measured potency values in %LC
LeBlond, D., Griffith, D. and Aubuchon, K. Linear Regression 102: Stability Shelf Life Estimation Using Analysis of Covariance. J Valid Technol (2011) 17(3): 47-68.