Computes the power for the unstratified (ordinary) logrank statistic
for two group comparison.
Usage
lgrkPower(hr, nevent, alpha = 0.05, rprob = 0.5)
Arguments
hr
hazard ratio
nevent
expected number of events
alpha
two-sided significance level
rprob
randomization probability
Value
power
logrank power
Details
Uses the formula at the bottom of p.317 from Schoenfeld (Biometrika, 1981)
where the beta should be 1 - beta. The formula is modified
to assume that values of the hazard ratio
less than 1 correspond to treatment efficacy. We do this because we only want
to include the probability of rejecting the null in favor of efficacy, not inferiority
as well.
References
Schoenfeld, D. The asymptotic properties of nonparametric tests for comparing
survival distributions. Biometrika. 1981; 68: 316-319.