flexmix (version 2.0-1)

trypanosome: Trypanosome

Description

Trypanosome data from a dosage-response analysis to assess the proportion of organisms belonging to different populations. It is assumed that organisms belonging to different populations are indistinguishable other than in terms of their reaction to the stimulus.

Usage

data("trypanosome")

source

R. Ashford and P.J. Walker (1972): Quantal Response Analysis for a Mixture of Populations. Biometrics 28, pages 981-988.

Details

The experimental technique involved inspection under the microscope of a representative aliquot of a suspension, all organisms appearing within two fields of view being classified either alive or dead. Hence the total numbers of organisms present at each dose and the number showing the quantal response were both random variables.

References

D.A. Follmann and D. Lambert (1989): Generalizing Logistic Regression by Nonparametric Mixing. Journal of the American Statistical Association 84(405), pages 195-300.

Examples

data("trypanosome")
trypMix <- stepFlexmix(cbind(Dead, 1-Dead) ~ 1, k = 2, 
	               nrep=5, data = trypanosome,
	               model = FLXMRglmfix(family = "binomial", fixed = ~log(Dose)))