flexmix (version 2.2-11)

betablocker: Clinical trial of beta-blockers

Description

22-centre clinical trial of beta-blockers for reducing mortality after myocardial infarction.

Usage

data("betablocker")

source

G. McLachlan and D. Peel (2000): Finite Mixture Models. John Wiley and Sons Inc. http://www.maths.uq.edu.au/~gjm/DATA/mmdata.html

References

M. Aitkin (1999): Meta-analysis by random effect modelling in generalized linear models. Statistics in medicine 18, pages 2343-2351.

S. Yusuf, R. Peto, J. Lewis, R. Collins and P. Sleight (1985): Beta blockade during and after myocardial infarction: an overview of the randomized trials. Progress in Cardiovascular Diseases 27, pages 335-371.

Examples

data("betablocker")
betaMix <- stepFlexmix(cbind(Deaths, Total-Deaths) ~ 1 | Center,
                       data=betablocker, k=3, nrep=5,
                       model=FLXMRglmfix(family="binomial",
                         fixed=~Treatment))