flexmix (version 2.3-9)

Mehta: Mehta Trial

Description

For a 22-centre trial the number of responses and the total number of patients is reported for the control group and the group receiving a new drug.

Usage

data("Mehta")

source

M. Aitkin. Meta-analysis by random effect modelling in generalized linear models. Statistics in Medicine, 18, 2343--2351, 1999.

References

C.R. Mehta, N.R. Patel and P. Senchaudhuri. Importance sampling for estimating exact probabilities in permutational inference. Journal of the American Statistical Association, 83, 999--1005, 1988.

Examples

data("Mehta", package = "flexmix")
mehtaMix <- initFlexmix(cbind(Response, Total-Response) ~ 1|Site, 
                     data=Mehta, nrep=5, k=3,
                     model=FLXMRglmfix(family="binomial",
                       fixed=~ Drug), 
                     control=list(minprior=0.04))

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