quick_km_band_plot

Convenience wrapper with sensible defaults for quick visualization.

internal

Implements statistical methods for exploratory subgroup identification
in clinical trials with survival endpoints. Provides tools for identifying
patient subgroups with differential treatment effects using machine learning
approaches including Generalized Random Forests (GRF), LASSO regularization,
and exhaustive combinatorial search algorithms. Features bootstrap bias
correction using infinitesimal jackknife methods to address selection bias
in post-hoc analyses. Designed for clinical researchers conducting exploratory
subgroup analyses in randomized controlled trials, particularly for
multi-regional clinical trials (MRCT) requiring regional consistency
evaluation. Supports both accelerated failure time (AFT) and Cox proportional
hazards models with comprehensive diagnostic and visualization tools.
Methods are described in León et al. (2024) <doi:10.1002/sim.10163>.

Larry Leon

forestsearch

Exploratory Subgroup Identification in Clinical Trials with
Survival Endpoints

quick_km_band_plot function

<dl><dt>df</dt>
<dd>Data frame with analysis data.</dd>
<dt>fs.est</dt>
<dd>ForestSearch result object.</dd>
<dt>outcome.name</dt>
<dd>Character. Time-to-event column name.</dd>
<dt>event.name</dt>
<dd>Character. Event indicator column name.</dd>
<dt>treat.name</dt>
<dd>Character. Treatment column name.</dd>
<dt>...</dt>
<dd>Additional arguments passed to <code>plot_km_band_forestsearch()</code>,
such as <code>ref_subgroups</code>, <code>tau_add</code>, <code>by_risk</code>, etc.</dd></dl>

Arguments

Quick Plot KM Bands from ForestSearch — quick_km_band_plot

<dl>

<dt>df</dt>
<dd>Data frame with analysis data.</dd>


<dt>fs.est</dt>
<dd>ForestSearch result object.</dd>


<dt>outcome.name</dt>
<dd>Character. Time-to-event column name.</dd>


<dt>event.name</dt>
<dd>Character. Event indicator column name.</dd>


<dt>treat.name</dt>
<dd>Character. Treatment column name.</dd>


<dt>...</dt>
<dd>Additional arguments passed to <code>plot_km_band_forestsearch()</code>,
such as <code>ref_subgroups</code>, <code>tau_add</code>, <code>by_risk</code>, etc.</dd>

</dl>

quick_km_band_plot: Quick Plot KM Bands from ForestSearch

Description

Usage

Value

Arguments