gap (version 1.1-1)

pgc: Preparing weight for GENECOUNTING

Description

This function is a R port of the GENECOUNTING/PREPARE program which takes an array of genotyep data and collapses individuals with the same multilocus genotype. This function can also be used to prepare for the genotype table in testing Hardy-Weinberg equilibrium.

Usage

pgc(data,handle.miss=1,is.genotype=0,with.id=0)

Arguments

data

the multilocus genotype data for a set of individuals

handle.miss

a flag to indicate if missing data is kept, 0 = no, 1 = yes

is.genotype

a flag to indicate if the data is already in the form of genotype identifiers

with.id

a flag to indicate if the unique multilocus genotype identifier is generated

Value

• The returned value is a list containing:
• cdata
  the collapsed genotype data
• wt
  the frequency weight
• obscom
  the observed number of combinations or genotypes
• idsave
  optional, available only if with.id = 1

References

Zhao JH, Sham PC (2003). Generic number system and haplotype analysis. Comp Prog Meth Biomed 70:1-9

See Also

genecounting,hwe.hardy

Examples

data(hla)
x <- hla[,3:8]

# do not handle missing data
y<-pgc(x,handle.miss=0,with.id=1)
hla.gc<-genecounting(y$cdata,y$wt,handle.miss=0)

# handle missing but with multilocus genotype identifier
pgc(x,handle.miss=1,with.id=1)

# handle missing data with no identifier
pgc(x,handle.miss=1,with.id=0)