calc_sigma

<p>eigenvalues vector from decomposition of relatedness matrix</p>

eval

OmegaU

OmegaE

UltVeh

<p>Calculate Sigma_ee and Sigma_uu matrices</p>

Fits a multivariate linear mixed effects model that uses a polygenic term, after Zhou & Stephens (2014) (<https://www.nature.com/articles/nmeth.2848>). Of particular interest is the estimation of variance components with restricted maximum likelihood (REML) methods. Genome-wide efficient mixed-model association (GEMMA), as implemented in the package 'gemma2', uses an expectation-maximization algorithm for variance components inference for use in quantitative trait locus studies.

calc_sigma: Calculate Sigma_ee and Sigma_uu matrices

Description

Usage

Arguments