update_v

<p>vector of eigenvalues from eigendecomposition of relatedness matrix</p>

eval

Sigma_uu

Sigma_ee

<p>a positive number indicating tolerance to be passed to isSymmetric()</p>

Fits a multivariate linear mixed effects model that uses a polygenic term, after Zhou & Stephens (2014) (<https://www.nature.com/articles/nmeth.2848>). Of particular interest is the estimation of variance components with restricted maximum likelihood (REML) methods. Genome-wide efficient mixed-model association (GEMMA), as implemented in the package 'gemma2', uses an expectation-maximization algorithm for variance components inference for use in quantitative trait locus studies.

update_v: Update V_e and V_g

Description

Usage

Arguments

See Also