calcGC2: Calculate GC Percentage in sliding window
Description
Local GC content can be used to remove GC artifacts from copynumber data
(see Diskin et al, Nucleic Acids Research, 2008, PMID: 18784189). This
function will calculate GC content fraction in expanded windows around
a set of ranges following example in
http://www.bioconductor.org/help/course-materials/2012/useR2012/Bioconductor-tutorial.pdf.
Values are as.integer( 1e4 * fraction ) for space reasons.
Usage
calcGC2(dna)
Arguments
dna
BSgenome or DNAStringSet
Value
SimpleRleList, integer 1e4 * GC fraction, chromosomes 1:22, X and Y