gestate (version 1.3.2)

frontierpower: Calculate Frontier power from number of events

Description

Calculate Frontier power from number of events

Usage

frontierpower(events, HR, Eratio, Rratio = 1, startpower = 0.5,
  alpha1 = 0.025, iter = 10)

Arguments

events

Number of events.

HR

Hazard Ratio. Values below 1 indicate a benefit to the active arm vs control.

Eratio

Event ratio.

Rratio

Randomisation ratio. Default=1.

startpower

Initial estimate of power. Default=0.5.

alpha1

1-sided alpha. Default=0.025.

iter

Number of iterations to perform. Default=10.

Value

Power as a decimal

References

Bell J, Power Calculations for Time-to-Event Trials Using Predicted Event Proportions, 2019, paper under review.

Examples

# NOT RUN {
frontierpower(events=300,HR=0.7,Eratio=1.2,Rratio=1.5,alpha1=0.025)
# }