munich2019dataset

The dataset contains data from 60 patients, treated at the 2 hospitals
Klinikum rechts der Isar (TUM) and Klinikum Bogenhausen (STKM),
Munich, Germany. 
It focuses on the prognostic impact of cytosolic Hsp70 (cHsp70) expression
and MGMT promoter methylation status.

datasets

Provides functions to load and analyze three open Electronic
Health Records (EHRs) datasets of patients diagnosed with
glioblastoma, previously released under the Creative Common
Attribution 4.0 International (CC BY 4.0) license. Users can generate
basic descriptive statistics, frequency tables and save descriptive
summary tables, as well as create and export univariate or bivariate
plots. The package is designed to work with the included datasets and
to facilitate quick exploratory data analysis and reporting. More
information about these three datasets of EHRs of patients with
glioblastoma can be found in this article: Gabriel Cerono, Ombretta
Melaiu, and Davide Chicco, 'Clinical feature ranking based on ensemble
machine learning reveals top survival factors for glioblastoma
multiforme', Journal of Healthcare Informatics Research 8, 1-18 (March
2024). <doi:10.1007/s41666-023-00138-1>.

Samuele Marelli

glioblastomaEHRsData

Descriptive Analysis on Three Glioblastoma EHRs Datasets

Davide Chicco

munich2019dataset function

A data frame with 60 rows and 8 variables:<dl>
 <dt>age_years</dt>
<dd>Numeric. Patient's age in years.</dd> <dt>cHsp70_low0_high1</dt>
<dd>Factor. "Low" (0) or "High" (1) cytosolic Hsp70 expression.</dd> <dt>MGMTmethylation_methylated1_unmethylated0</dt>
<dd>Factor "unmethylated" (0) or "methylated" (1) MGMT promoter.</dd> <dt>OS_months</dt>
<dd>Numeric. Overall survival in months.</dd> <dt>PFS_months</dt>
<dd>Numeric. Progression-free survival in months.</dd> <dt>sex_male0_female1</dt>
<dd>Factor. "Male" (0) or "Female" (1).</dd> <dt>survived_yes1_no0</dt>
<dd>Factor. "Dead" (0) or "Alive" (1) at their most recent check-up.</dd> <dt>tumor_progression_yes1_no0</dt>
<dd>Factor. "No" (0) or "Yes" (1) for tumor progression after treatment.</dd>
</dl>

Format

The dataset contains data from 60 patients, treated at the 2 hospitals
Klinikum rechts der Isar (TUM) and Klinikum Bogenhausen (STKM),
Munich, Germany. 
It focuses on the prognostic impact of cytosolic Hsp70 (cHsp70) expression
and MGMT promoter methylation status.

EHR data of patients affected by Glioblastoma (GBM), collected from Munich, Germany. — munich2019dataset

A data frame with 60 rows and 8 variables:<dl>
 <dt>age_years</dt>
<dd>Numeric. Patient's age in years.</dd>

 <dt>cHsp70_low0_high1</dt>
<dd>Factor. "Low" (0) or "High" (1) cytosolic Hsp70 expression.</dd>

 <dt>MGMTmethylation_methylated1_unmethylated0</dt>
<dd>Factor "unmethylated" (0) or "methylated" (1) MGMT promoter.</dd>

 <dt>OS_months</dt>
<dd>Numeric. Overall survival in months.</dd>

 <dt>PFS_months</dt>
<dd>Numeric. Progression-free survival in months.</dd>

 <dt>sex_male0_female1</dt>
<dd>Factor. "Male" (0) or "Female" (1).</dd>

 <dt>survived_yes1_no0</dt>
<dd>Factor. "Dead" (0) or "Alive" (1) at their most recent check-up.</dd>

 <dt>tumor_progression_yes1_no0</dt>
<dd>Factor. "No" (0) or "Yes" (1) for tumor progression after treatment.</dd>


</dl>

munich2019dataset: EHR data of patients affected by Glioblastoma (GBM), collected from Munich, Germany.

Description

Usage

Arguments

Format

References

Examples