glmtoolbox (version 0.1.12)

bladder: Bladder cancer in mice

Description

Female mice were continuously fed dietary concentrations of 2-Acetylaminofluorene (2-AAF), a carcinogenic and mutagenic derivative of fluorene. Serially sacrificed, dead or moribund mice were examined for tumors and deaths dates recorded. These data consist of the incidences of bladder neoplasms in mice observed during 33 months.

Usage

data(bladder)

Format

A data frame with 8 rows and 3 variables:

dose

a numeric vector giving the dose, in parts per \(10^4\), of 2-AAF.

exposed

a numeric vector giving the number of mice exposed to each dose of 2-AAF.

cancer

a numeric vector giving the number of mice with bladder cancer for each dose of 2-AAF.

References

Zhang H., Zelterman D. (1999) Binary Regression for Risks in Excess of Subject-Specific Thresholds. Biometrics 55:1247-1251.

See Also

liver

Examples

data(bladder)
dev.new()
barplot(100*cancer/exposed ~ dose, beside=TRUE, data=bladder, col="red",
        xlab="Dose of 2-AAF", ylab="% of mice with bladder cancer")