mammary: Ability of retinyl acetate to prevent mammary cancer in rats
Description
A total of 76 female rats were injected with a carcinogen
for mammary cancer. Then, all animals were given retinyl acetate
(retinoid) to prevent mammary cancer for 60 days. After this phase,
the 48 animals that remained tumor-free were randomly assigned to
continue retinoid prophylaxis or control. Rats were then palpated for
tumors twice weekly, and observations ended 182 days after initial
carcinogen injections began. The main objective of the analysis was
to assess the difference in tumor development between the treated
and control groups.
Usage
data(mammary)
Arguments
Format
A data frame with 48 rows and 2 variables:
group
a factor giving the group to which the rat was assigned: "retinoid" or "control".
tumors
a numeric vector giving the number of tumors identified on the rat.
References
Lawless J.F. (1987) Regression Methods for Poisson Process Data. Journal of the American
Statistical Association 82:808-815.
Morel J.G., Nagaraj N.K. (2012) Overdispersion Models in SAS. SAS Institute Inc., Cary, North Carolina, USA.