grantham_distance_original

This function calculates the Grantham's distance for pairs of amino acids. It
uses the pre-calculated distances for each amino acid pair as published in
Table 2 of Science (1974). 185(4154): 862--4 by R. Grantham.

internal

A minimal set of routines to calculate the Grantham distance
<doi:10.1126/science.185.4154.862>. The Grantham distance attempts to
provide a proxy for the evolutionary distance between two amino acids
based on three key chemical properties: composition, polarity and
molecular volume. In turn, evolutionary distance is used as a proxy for
the impact of missense mutations. The higher the distance, the more
deleterious the substitution is expected to be.

Ramiro Magno

grantham

Calculate the Grantham Distance

Isabel Duarte

Ana-Teresa Maia

University of Algarve 

CINTESIS 

Pattern Institute 

grantham_distance_original function

<dl><dt>x</dt>
<dd>A character vector of amino acid three-letter codes.</dd>
<dt>y</dt>
<dd>A character vector of amino acid three-letter codes.</dd></dl>

Arguments

Grantham's distance (original) — grantham_distance_original

<dl>

<dt>x</dt>
<dd>A character vector of amino acid three-letter codes.</dd>


<dt>y</dt>
<dd>A character vector of amino acid three-letter codes.</dd>

</dl>

grantham_distance_original: Grantham's distance (original)

Description

Usage

Value

Arguments