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grouprar (version 0.1.0)

Group Response Adaptive Randomization for Clinical Trials

Description

Implement group response-adaptive randomization procedures, which also integrates standard non-group response-adaptive randomization methods as specialized instances. It is also uniquely capable of managing complex scenarios, including those with delayed and missing responses, thereby expanding its utility in real-world applications. This package offers 16 functions for simulating a variety of response adaptive randomization procedures. These functions are essential for guiding the selection of statistical methods in clinical trials, providing a flexible and effective approach to trial design. Some of the detailed methodologies and algorithms used in this package, please refer to the following references: LJ Wei (1979) L. J. WEI and S. DURHAM (1978) Durham, S. D., FlournoY, N. AND LI, W. (1998) Ivanova, A., Rosenberger, W. F., Durham, S. D. and Flournoy, N. (2000) Bai Z D, Hu F, Shen L. (2002) Ivanova, A. (2003) Hu, F., & Zhang, L. X. (2004) Hu, F., & Rosenberger, W. F. (2006, ISBN:978-0-471-65396-7). Zhang, L. X., Chan, W. S., Cheung, S. H., & Hu, F. (2007) Zhang, L., & Rosenberger, W. F. (2006) Hu, F., Zhang, L. X., Cheung, S. H., & Chan, W. S. (2008) .

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Version

Install

install.packages('grouprar')

Monthly Downloads

163

Version

0.1.0

License

GPL (>= 2)

Maintainer

Guannan Zhai

Last Published

March 4th, 2024

Functions in grouprar (0.1.0)

Group.dyldDBCD_Cont

Group Doubly Biased Coin Design with Delayed Continuous Response
DBCD_Bin

Hu and Zhang's Doubly Biased Coin Design with Binary Response Type
Bai Hu Shen's Urn

Bai Hu Shen's Urn
Group.DBCD_Cont

Group Doubly Biased Coin Design with Continuous Response Type
Group.dyldDBCD_Bin

Group Doubly Biased Coin Design with Delayed Discrete Response
PolyaUrn

Randomized Pólya urn procedure
WeiUrn

Randomized Play-the-winner rule with multiple arms (\(k > 2\))
grouprar

grouprar-package: Group Response-Adaptive Randomization for Clinical Trials
DBCD_Cont

Hu and Zhang's Doubly Biased Coin Design with Continuous Response Type
RPWRule

Randomized Play-the-winner Rule
dyldDBCD_Bin

Hu and Zhang's Doubly Biased Coin Deisgn with delayed Binary Response
dyldDBCD_Cont

Hu and Zhang's Doubly Biased Coin Deisgn with delayed Continuous Response
Group.DBCD_Bin

Group Doubly Biased Coin Design with Binary Response Type
GDLRule

Generalized drop-the-loser rule
DLRule

Drop the loser rule
CRDesign

Complete Randomization
BirthDeathUrn

Birth and Death Urn