get_combo_power

A helper function passed to <code><a href="/link/uniroot()?package=gsDesign2&version=1.1.2" data-mini-rdoc="gsDesign2::uniroot()">uniroot()</a></code>

internal

The goal of 'gsDesign2' is to enable fixed or group sequential
design under non-proportional hazards. To enable highly flexible enrollment,
time-to-event and time-to-dropout assumptions, 'gsDesign2' offers piecewise
constant enrollment, failure rates, and dropout rates for a stratified
population. This package includes three methods for designs:
average hazard ratio, weighted logrank tests in Yung and Liu (2019)
<doi:10.1111/biom.13196>, and MaxCombo tests.
Substantial flexibility on top of what is in the 'gsDesign' package
is intended for selecting boundaries.

Yujie Zhao

gsDesign2

Group Sequential Design with Non-Constant Effect

Keaven Anderson

Yilong Zhang

Jianxiao Yang

Nan Xiao

Amin Shirazi

Ruixue Wang

Yi Cui

Ping Yang

Xin Tong Li

Chenxiang Li

Hiroaki Fukuda

Hongtao Zhang

Yalin Zhu

John Blischak

Dickson Wanjau

Merck & Co., Inc., Rahway, NJ, USA and its affiliates 

get_combo_power function

<dl><dt>n</dt>
<dd>Input sample size</dd>
<dt>algorithm</dt>
<dd>an object of class <code><a href="/link/GenzBretz?package=gsDesign2&version=1.1.2" data-mini-rdoc="gsDesign2::GenzBretz">GenzBretz</a></code>,
 <code><a href="/link/Miwa?package=gsDesign2&version=1.1.2" data-mini-rdoc="gsDesign2::Miwa">Miwa</a></code> or <code><a href="/link/TVPACK?package=gsDesign2&version=1.1.2" data-mini-rdoc="gsDesign2::TVPACK">TVPACK</a></code>
 specifying both the algorithm to be used as well as
 the associated hyper parameters.</dd>
<dt>beta</dt>
<dd>Type II error.</dd>
<dt>...</dt>
<dd>Additional parameters passed to <a href="/link/mvtnorm%3A%3Apmvnorm?package=gsDesign2&version=1.1.2" data-mini-rdoc="gsDesign2::mvtnorm::pmvnorm">mvtnorm::pmvnorm</a>.</dd></dl>

Arguments

A helper function passed to <code><a href='https://rdrr.io/r/stats/uniroot.html'>uniroot()</a></code>

Function to calculate power — get_combo_power

<dl>

<dt>n</dt>
<dd>Input sample size</dd>


<dt>algorithm</dt>
<dd>an object of class <code><a href='https://rdrr.io/pkg/mvtnorm/man/algorithms.html'>GenzBretz</a></code>,
 <code><a href='https://rdrr.io/pkg/mvtnorm/man/algorithms.html'>Miwa</a></code> or <code><a href='https://rdrr.io/pkg/mvtnorm/man/algorithms.html'>TVPACK</a></code>
 specifying both the algorithm to be used as well as
 the associated hyper parameters.</dd>


<dt>beta</dt>
<dd>Type II error.</dd>


<dt>...</dt>
<dd>Additional parameters passed to <a href='https://rdrr.io/pkg/mvtnorm/man/pmvnorm.html'>mvtnorm::pmvnorm</a>.</dd>

</dl>

Function to calculate power

get_combo_power: Function to calculate power

Description

Usage

Value

Arguments

Details