Quality of life scores for 175 participants, from a randomized controlled trial,
at 2, 4 and 8 weeks after treatment.

datasets

Methods to construct and power group sequential clinical trial
designs for outcomes at multiple times. Outcomes at earlier times provide
information on the final (primary) outcome. A range of recruitment and
correlation models are available as are methods to simulate data in order to
explore design operating characteristics. For more details see Parsons (2024)
<doi:10.1186/s12874-024-02174-w>.

Nick Parsons

gsearly

Creates Group Sequential Trial Designs when Early Outcomes are
Available

qol function

A data frame with 455 observations on the following four variables.<dl>
 <dt><code>Subject</code></dt>
<dd>A participant identifier variable.</dd> <dt><code>Weeks</code></dt>
<dd>Recorded at follow-up times of 2, 4 and 8 weeks.</dd> <dt><code>STime</code></dt>
<dd>Standardized follow-up time variable; see
 <code>tfuStandard</code>.</dd> <dt><code>Treat</code></dt>
<dd>Random treatment allocation (A or B).</dd> <dt><code>QoL</code></dt>
<dd>Quality of life index (0-100), where a higher value
 indicates a higher QoL.</dd> <dt><code>Day</code></dt>
<dd>Day number (starting at 1), when QoL was assessed.</dd> 
</dl>

Format

Quality of life index for patients with knee pain — qol

A data frame with 455 observations on the following four variables.<dl>
 <dt><code>Subject</code></dt>
<dd>A participant identifier variable.</dd>

 <dt><code>Weeks</code></dt>
<dd>Recorded at follow-up times of 2, 4 and 8 weeks.</dd>

 <dt><code>STime</code></dt>
<dd>Standardized follow-up time variable; see
 <code>tfuStandard</code>.</dd>

 <dt><code>Treat</code></dt>
<dd>Random treatment allocation (A or B).</dd>

 <dt><code>QoL</code></dt>
<dd>Quality of life index (0-100), where a higher value
 indicates a higher QoL.</dd>

 <dt><code>Day</code></dt>
<dd>Day number (starting at 1), when QoL was assessed.</dd>

 
</dl>

qol: Quality of life index for patients with knee pain

Description

Usage

Arguments

Format

Examples