grs.filter.Qrs

aligned beta coefficients in the testing dataset

p.thresh

Performs a stepwise downward "model selection" in which SNPs are
  iteratively removed from the risk score until the heterogeneity test
  is no longer significant at the specified threshold.

Assorted tools for genetic association analyses.  The focus is on implementing (either exactly or approximately) regression analyses using summary statistics instead of using subject-specific data.  So far, functions exist to support multi-SNP risk score analyses, and multi-SNP conditional regression analyses, using summary statistics.  There are helper functions for reading and manipulating subject-specific genotype data, which provide a platform for calculating the summary statistics, or for using R to conduct other analyses not supported by specific GWAS analysis tools.

grs.filter.Qrs: Filter SNPs for inclusion in genetic risk score using heterogeneity test.

Description

Usage

Arguments

Details