make.v

Not to be called directly. Used by <code>eff.sigma</code>,
<code>eff.mu</code>,
<code>eff.rho</code>,
<code>pp.sigma</code>,
<code>pp.mu</code>, and 
<code>pp.rho</code>.

misc

Calculate expected relative risk and proportion protected assuming normally distributed log10 transformed antibody dose for a several component vaccine. Uses Hill models for each component which are combined under Bliss independence. See Saul and Fay, 2007 <DOI:10.1371/journal.pone.0000850>.

Michael Fay

hbim

Hill/Bliss Independence Model for Combination Vaccines

make.v function

<dl> <dt>n</dt>
<dd>dimension of variance matrix</dd> <dt>r</dt>
<dd>correlation</dd> <dt>sig2</dt>
<dd>variance</dd></dl>

Arguments

Make Exchangeable Variance Matrix — make.v

<dl>

 <dt>n</dt>
<dd>dimension of variance matrix</dd>

 <dt>r</dt>
<dd>correlation</dd>

 <dt>sig2</dt>
<dd>variance</dd>

</dl>

make.v: Make Exchangeable Variance Matrix

Description

Usage

Value

Arguments