Calculate expected relative risk and proportion protected assuming normally distributed log10 transformed antibody dose for several component vaccine. Uses Hill models for each component which are combined under Bliss independence.
M.P. Fay, Maintainer: Michael Fay <mfay@niaid.nih.gov>
| Package: | hbim |
| Type: | Package |
| Version: | 1.0 |
| Date: | 2022-05-09 |
| License: | GPL |
The hbim package allows users to reproduce plots and calculations for Saul and Fay (2007). See vignette("hbimdetails").
Saul A, Fay MP (2007). Human Immunity and the Design of Multi-Component, Single Target Vaccines. PLoS ONE 2(9): e850. doi:10.1371/jounal.pone.0000850