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hce

Simulate and analyze hierarchical composite endpoints

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You can install hce from CRAN:

install.packages("hce")

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install.packages('hce')

Monthly Downloads

393

Version

0.6.7

License

MIT + file LICENSE

Maintainer

Samvel B. Gasparyan

Last Published

January 7th, 2025

Functions in hce (0.6.7)

calcWINS.data.frame

Win statistics calculation using a data frame
calcWINS.hce

Win statistics calculation for hce objects
hce

Helper function for hce objects
calcWO.hce

Win odds calculation for hce objects
calcWO

A generic function for calculating win odds
minWO

Minimum detectable or WO for alternative hypothesis for given power (no ties)
calcWINS

A generic function for calculating win statistics
plot.hce_results

A print method for hce_results objects
calcWO.data.frame

Win odds calculation using a data frame
calcWO.formula

Win odds calculation using formula syntax
as_hce.data.frame

Coerce a data frame to an hce object
plot.hce

A plot method for hce objects
as_hce

A generic function for coercing data structures to hce objects
powerWO

Power calculation for the win odds test (no ties)
KHCE

Kidney Hierarchical Composite Endpoint dataset.
regWO.data.frame

Win odds regression using a data frame
regWO

A generic function for win odds regression
stratWO.data.frame

Stratified win odds with adjustment
sizeWR

Sample size calculation for the win ratio test (with WR = 1 null hypothesis)
simHCE

Simulate hce object with given event rates of time-to-event outcomes (Weibull), mean and SD of the continuous outcome (normal or log-normal) by treatment group
simADHCE

Simulate adhce object with given event rates of time-to-event outcomes (Weibull), mean and SD of the continuous outcome (normal or log-normal) by treatment group
simORD

Simulate ordinal variables for two treatment groups using categorization of beta distributions
calcWINS.formula

Win statistics calculation using formula syntax
summaryWO

A generic function for summarizing win odds
stratWO

A generic function for stratified win odds with adjustment
print.hce_results

A print method for hce_results objects
sizeWO

Sample size calculation for the win odds test (no ties)
propWINS

Proportion of wins/losses/ties given the win odds and the win ratio
summaryWO.data.frame

Win odds summary for a data frame
summaryWO.formula

Win odds summary using formula syntax
summaryWO.hce

Win odds summary for hce objects
ADSL

Baseline characteristics dataset of patients with kidney function assessments.
COVID19plus

COVID-19 ordinal scale dataset for a combination therapy.
ADLB

Laboratory dataset for Glomerular Filtration Rate (GFR) measurements.
COVID19

COVID-19 ordinal scale dataset (full report).
ADET

Event-Time dataset for kidney outcomes.
HCE1

HCE1, HCE2, HCE3, HCE4 datasets for 1000 patients with different treatment effects.
HCE4

HCE1, HCE2, HCE3, HCE4 datasets for 1000 patients with different treatment effects.
COVID19b

COVID-19 ordinal scale dataset (preliminary report).
HCE3

HCE1, HCE2, HCE3, HCE4 datasets for 1000 patients with different treatment effects.
HCE2

HCE1, HCE2, HCE3, HCE4 datasets for 1000 patients with different treatment effects.