hctrial

hctrial provides functions for designing phase II clinical trials adjusting for the heterogeneity of the population using known subgroups or historical controls

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Install

install.packages('hctrial')

Monthly Downloads

159

Version

0.1.0

License

GPL-2 | GPL-3

Maintainer

Dominic Edelmann

Last Published

December 21st, 2018

Functions in hctrial (0.1.0)

hctrial

hctrial: A package for designing phase 2 clinical trials adjusting for heterogeneous populations.

strat_end

Adjust a subspace stratified design at the end of the study.

strat_interim

Adjust a subspace stratified design at interim.

strat_start

Initializes a subspace stratified design before the start of the study.

hist_interim

Adjust a design based on historical controls at interim using the covariate data of the patients accrued in stage 1.

hist_start

Initializes a design based on historical controls before the start of the study.

hist_end

Adjust a design based on historical controls at the end of the study using the covariate data of the patients accrued in stage 2.